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Skullcap
(Scutellaria lateriflora)
Description
European skullcap is not to be confused with its Chinese relative,
Scutellaria baicalensis, a common herb used in Chinese herbal
formulas. The two herbs have very different effects on the
body. One way to tell the difference is that the above-ground
plant of European skullcap is used, while the root of the
Chinese herb is used. European skullcap is popularly used
as a sedative.
Herbal Uses
Traditionally, Native Americans
and European herbalists used skullcap as a sedative. It has
been used to induce sleep, and relieve Nervousness.
Suggested Intakes
1 to 2 g, three times a
day.
When taken in combination
with other herbs, follow label instructions.
Usually, skullcap is not
taken long-term.
Supplemental Uses
Sedative:
Today, skullcap is still commonly used as a sedative, although
little scientific evidence exists to support its use. Skullcap
may have mild sedative and antispasmodic properties (1). It
appears to alleviate mild Anxiety and Insomnia. Skullcap has
also been used to facilitate drug or alcohol withdrawal.
Safety and Precautions
The safety of skullcap is
relatively unknown. One study has indicated that excessive
amounts can cause confusion and stupor (2). Some products
containing skullcap have caused liver damage. However, it
is very likely that the germander commonly contaminating skullcap
is the culprit. Germander is a known toxic substance to the
liver.
Safety in young children,
pregnant or nursing women, and patients with severe liver
or kidney disease has not been determined. It is therefore
not advised for these individuals.
Interactions and Contra-Indications
Skullcap may interact with
alkaloids, anorectic drugs (fenfluramine), dopamine receptor
agonists, oral anticoagulants, analgesics (nalbuphine HCl
and propoxyphene HCl), CNS drugs, furosemide, and colchicine.
It may increase the metabolism
of digitoxin, oral contraceptives, phenytoin, corticosteroids,
fluroxene, methadone, metyrapone, and tetracyclines.
Avoid use with methotrimeprazine,
a CNS depressant analgesic, and procarbazine antineoplastic
drugs.
References
1. Foster S. herbs for Your
Health. Loveland, CO: Interweave Press, 1996, 86-87.
2. Newall C, et al. Herbal medicines: A guide for health-care
professionals. London: Pharmaceutical Press, 1996: 239. | 
